| Polokwane Mankweng Hospital Complex | Institutional | Visit the institution's website  |
| Medical and Research Ethics Committee | Private | Visit the institution's website  |
| 1 Military Hospital REC - 1 Military Hospital, Pretoria | Institutional | Visit the institution's website  |
| Biomedical Research Ethics Committee (BREC) - University of KwaZulu-Natal | Institutional | Visit the institution's website  |
| Ekurhleni Metropolitan Municipality Research ethics committee - Ekurhleni Metropolitan Municipality | Institutional | Visit the institution's website  |
| Ethics Committee of the Faculty of Health Sciences - University of the Free State | Institutional | Visit the institution's website  |
| Faculty of Health Science Research Ethics Committee - University of Pretoria | Institutional | Visit the institution's website  |
| Faculty of Health Sciences Research Committee - Durban University of Technology | Institutional | Visit the institution's website  |
| Faculty of Health Sciences Research Ethics Committee - University of Cape Town | Institutional | Visit the institution's website  |
| Health and Wellness Sciences Research Ethics Committee - Cape Peninsula University of Technology | Institutional | Visit the institution's website  |
| Health Research Ethics & Biosafety Committee - Walter Sisulu University, Faculty of Health Sciences | Institutional | Visit the institution's website  |
| Health Research Ethics Committee 1 - Stellenbosch University, Faculty of Health Sciences | Institutional | Visit the institution's website  |
| Health Research Ethics Committee 2 - Stellenbosch University, Faculty of Health Sciences | Institutional | Visit the institution's website  |
| HPCA Research Ethics Committee - Hospice Palliative Care Association (HPCA) | Private | Visit the institution's website  |
| HSRC Research Ethics Committee - Human Sciences Research Council (HSRC) | Institutional | Visit the institution's website  |
| Human Research Ethics Committee (Medical) - University of the Witwatersrand | Institutional | Visit the institution's website  |
| McCord Research Ethics Committee - McCord Hospital | Institutional | Visit the institution's website  |
| Medunsa Research Ethics Committee (MREC) - University of Limpopo (Medunsa Campus) | Institutional | Visit the institution's website  |
| NMMU Research Ethics Committee (Animal) (REC-A) - Nelson Mandela Metropolitan University | Institutional | Visit the institution's website  |
| NMMU Research Ethics Committee (Human) (REC-H) - Nelson Mandela Metropolitan University | Institutional | Visit the institution's website  |
| North-West Research Ethics Committee - University of North West | Institutional | Visit the institution's website  |
| Pharma-Ethics Independent Research Ethics Committee - Pharma-Ethics | Private | Visit the institution's website  |
| South African Medical Association Research Ethics Committee(SAMAREC) - South African Medical Association (SAMA) | National | Visit the institution's website  |
| South African National Blood Servics Human Reserach Ethica Committee - South African National Blood Service | Institutional | Visit the institution's website  |
| Tshwane University of Technology Research Ethics Committee - Tshwane University of Technology | Institutional | Visit the institution's website  |
| University of Cape Town Animal Research Ethics Committee - University of Cape Town | Institutional | Visit the institution's website  |
| University of Pretoria Faculty of Health Sciences Student Research ethics Committee - University of Pretoria | | Visit the institution's website  |